Well, they may not be problems for everyone – but they’re problems for me with the latest OS X client:

1. I can’t seem to turn off warning messages – like the one that tells me that I have multiple tabs open in a chat window.
2. I can’t seem to turn off cascading windows – I want my video chats to be in ONE position, period. This becomes a problem when…
3. When I’m in the middle of a call, new calls interrupt that call when I have Skype set to pick up all calls automatically. “That’s a feature, not a bug” – yeah, but Skype should be smart enough to understand that I’m already in the middle of a freakin’ call, man.
4. You can’t tweak the volume of a current call if the other side is sending video. At least, not that I have discovered.
5. This should go without saying, but the Skype Mac client is a distant second to the Windows version. I’m starting to understand the frustration Mac users have had all these years, and I’m about to become a LOT more vocal about it.
6. The login pane doesn’t adhere to the size I set for the client. If you’ve bothered to resize your contact list window, you’ll know what I’m talking about.
7. The menu bar icon doesn’t remain when you exit out of Skype. At least, if I’m offline, Skype should eliminate the icon from the Dock – or allow me to configure it that way.
8. There’s no “Mute All Sounds” toggle in the Notifications preference pane.
9. I can’t resize the PIP in a video call.
10. I can’t swap the PIP with the recipient’s video (since I use CamTwist with a chat overlay for my video source).